Welcome to Wei Li lab
A passion for understanding human genome functions with innovative AI, gene editing, and genomics technologies
We use novel computational, AI, and genome engineering approaches to understand the function of human genome, especially in the context of human physiology and disease.
What we do
The lab focuses on understanding how coding and non-coding elements in the genome function in human physiology and disease, and further identifying novel molecular targets to inform precision medicine. Our current projects involve cancer and cancer immunology (e.g., brain, breast, and pediatric cancers; T cell therapy), infectious diseases (e.g., HIV, RSV), and many genetic diseases.
How we do it
We are particularly interested in applying new genomics, gene editing, and ML/AI methods to address challenges in biomedical and biological big data problems. Technologies used in our lab include CRISPR-Cas9, Cas13, base editing, CRISPR screening, single-cell sequencing, Perturb-seq, deep learning, and other AI technologies.
Who we are
We are part of the Center for Genetic Medicine Research at Children’s National Hospital. We are also affiliated with Department of Genomics & Precision Medicine and Department of Pediatrics at The George Washington School of Medicine and Health Sciences.
“To infinity, and beyond!”
— Buzz Lightyear
Buzz Lightyear of Star Command: The Adventure Begins.
Welcome to Wei Li lab 